FVA
Flux variability analysis
FVA class
Performs flux variability analysis. It is based on the paper of (Gudmundsson and Thiele, Bioinformatics 2010).
See also:
Steinn Gudmundsson & Ines Thiele, Computationally efficient flux variability analysis, BMC Bioinformatics, volume 11, Article number: 489 (2010), https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-11-489
Input
Output
Configuration
biomass_optimization
Biomass optimization
string
maximize
minimize
fluxes_to_maximize
The fluxes to maximize
list
fluxes_to_minimize
The fluxes to minimize
list
solver
The optimization solver. It is recommended to use `quad`. Other solvers are in `beta` versions.
string
quad
highs-ds
highs-ipm
highs
interior-point
quad
relax_qssa
True to relaxing the quasi-steady state assumption (QSSA) constrain (`quad` solver is used). False otherwise.
bool
qssa_relaxation_strength
Used only if the QSSA is relaxed. The higher is the strength, the stronger is the QSSA. Hint: Set to the number of reactions to have strong QSSA contrain.
float
parsimony_strength
Set True to perform parsimonious FBA (pFBA). In this case the quad solver is used. Set False otherwise
float